1. There is a _______ (显著的,突出的) difference between Jane and Mary. 
2. Medicine should not be kept where it is _______ (容易取得的) to children. 
3. John was _______ (气喘吁吁的) after running for half a mile. 
4. Your suitcase is five kilograms _______ (超重), which is not allowed to be carried on board. 
5. The representative _______ (伴随着) his angry words with forceful movements of the hands.